GLP-1 medications work. That’s not the problem.
The problem is muscle loss when weight loss isn’t properly supported.
This guide explains:
- Why muscle loss happens on GLP-1s
- How to prevent it
- Protein targets that matter
- Training strategies that work
- The role of hormones
Why Muscle Loss Happens on GLP-1s
GLP-1s reduce appetite. That’s the point.
But reduced intake often leads to:
- Inadequate protein
- Lower training stimulus
- Caloric deficits that exceed recovery capacity
Weight loss without muscle preservation leads to worse long-term outcomes.
Protein Targets That Matter
Most people under-eat protein on GLP-1s.
General guideline:
- Prioritize protein at every meal
- Aim for sufficient intake relative to lean mass
Protein is non-negotiable for muscle retention.
Resistance Training Is Mandatory
Cardio does not preserve muscle.
Resistance training:
- Signals muscle retention
- Improves insulin sensitivity
- Protects metabolic rate
You don’t need intensity. You need consistency.
Hormone Optimization Matters
Low testosterone, estrogen imbalance, and cortisol issues increase muscle loss risk.
Hormone evaluation is often overlooked in GLP-1 protocols.
Conclusion
GLP-1 medications can support fat loss.
Muscle retention requires intention.
Without a plan, weight loss becomes body composition loss.
Comprehensive Weight Loss Plan
If you’re using or considering GLP-1 therapy, muscle preservation must be part of the strategy.
Book a comprehensive weight loss plan with 1st Optimal to protect muscle while losing fat.
