Testosterone Therapy for Women: What a 2026 Systematic Review Found About Libido and Sexual Function

Testosterone Therapy for Women: What a 2026 Systematic Review Found About Libido and Sexual Function

Author: Joe Miller, Founder of 1st Optimal Medically reviewed by: Franchell Hamilton, MD, FACS, FASMBS, DABOM Quick Answer: A 2026 systematic review found that testosterone therapy was associated with improvements in sexual desire, libido, sexual satisfaction, and satisfactory sexual experiences in women. The strongest evidence came from randomized clinical trials involving postmenopausal women. Results in […]

Can Women Continue Hormone Therapy After Age 60 or 65?

Can women stay on hormone therapy after 60 or 65? Learn when it may be appropriate, what risks matter, and why individualized care is key.

Some women can continue hormone therapy after age 60 or 65. The better question is not “What age should women stop?” It’s “Is hormone therapy still appropriate for this woman, with her symptoms, health history, risk factors, labs, and goals?” For many years, women were often told to stop hormone therapy automatically at age 60 […]

Menopause Skin Care Routine: What Changes After Estrogen Declines

Menopause Skin Care Routine: What Changes After Estrogen Declines

When estrogen drops during menopause, skin changes are not subtle. They are structural. Collagen declines, hydration falls, and the skin barrier becomes more fragile. What used to “work fine” in your 30s often stops working entirely. The goal is not just anti-aging. It is restoring skin function. This guide breaks down what actually changes in […]

Total Testosterone vs. Free Testosterone: Which Number Explains Symptoms Better?

Total Testosterone vs. Free Testosterone: Which Number Explains Symptoms Better?

Total testosterone is usually the starting point for evaluating testosterone status. Free testosterone may explain symptoms better when total testosterone looks “normal” but the patient still has symptoms, especially when sex hormone-binding globulin, or SHBG, is high or low. The real answer is this: symptoms, total testosterone, free testosterone, SHBG, and the full clinical picture […]

No Energy After 40: The Most Common Medical and Lifestyle Causes

No Energy After 40: The Most Common Medical and Lifestyle Causes

Feeling wiped out after 40 is common, but it’s not something you should automatically accept as “just aging.” Yes, life gets heavier. Work, parenting, stress, poor sleep, inconsistent training, and too much caffeine can all catch up with you. But persistent low energy can also be a signal that something deeper is going on. At […]

The First 10 Years After Menopause: Why Timing Matters With Hormone Therapy

The First 10 Years After Menopause: Why Timing Matters With Hormone Therapy

The first 10 years after menopause may be one of the most important windows for discussing hormone therapy. For many healthy women who are under age 60 or within 10 years of menopause, the benefit-to-risk profile of menopausal hormone therapy is often more favorable than it is when therapy is started later. That does not […]

How Do I Know if My Hormones Are Affecting My Energy and Focus?

How Do I Know if My Hormones Are Affecting My Energy and Focus?

If you’re sleeping, eating reasonably well, and still dragging yourself through the day, hormones may be part of the problem. Hormone-related fatigue rarely appears alone. It often shows up with brain fog, sleep changes, mood shifts, weight changes, altered menstrual cycles, reduced libido, or slower exercise recovery. The pattern matters more than any single symptom. […]

Is Hormone Therapy Safe for Women in Their 40s and 50s?

Is Hormone Therapy Safe for Women in Their 40s and 50s?

For many healthy women experiencing disruptive symptoms in their 40s and 50s, hormone therapy can be a safe and effective treatment. The safest approach depends on when treatment begins, the type and route of hormones used, whether a woman has a uterus, and her personal health history. Hormone therapy is not risk-free, but neither is […]

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Welcome to 1st Optimal

As a first-time member, enjoy 15% OFF your first purchase and take the first step toward personalized care designed around you.

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